Clinical Depression (“Major Depressive Disorder”) consists of some combination of the following symptoms: 1) Depressed mood most of every day; 2) Activities are no longer enjoyable/exciting; 3) Changes in weight or appetite (in either direction); 4) An observable slowing down (of thought or movement); 5) Fatigue or lost energy; 6) Feelings of worthlessness or guilt; 7) Problems concentrating or making decisions; 8) Thoughts of death and/or thoughts of suicide. People coping with depression can often get symptom relief in the short-run by being prescribed anti-depressant medication and can address depression more thoroughly with psychotherapy. Research shows a combined approach often works best.